2026-04-29T17:03:10Zhttps://repisalud.isciii.es/rest/oai/requestoai:repisalud.isciii.es:20.500.12105/129152024-10-31T11:56:25Zcom_20.500.12105_2052com_20.500.12105_2051col_20.500.12105_19609
Repisalud
author
Blanco Vázquez, Cristina
author
Barral, Thiago Doria
author
Romero, Beatriz
author
Queipo, Manuel
author
Merediz, Isabel
author
Quirós, Pablo
author
Armenteros, José Ángel
author
Juste, Ramón
author
Domínguez, Lucas
author
Dominguez-Rodriguez, Mercedes
author
Casais, Rosa
author
Balseiro, Ana
funder
Ministerio de Ciencia, Innovación y Universidades (España)
funder
Agencia Estatal de Investigación (España)
funder
Unión Europea. Fondo Europeo de Desarrollo Regional (FEDER/ERDF)
funder
Ministerio de Agricultura, Pesca y Alimentación (España)
funder
Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria (España)
funder
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (Brasil)
2021-05-09T14:43:27Z
2021-05-09T14:43:27Z
2021-04-30
Animals (Basel). 2021 Apr 30;11(5):1294.
10.3390/ani11051294
2076-2615
Animals
33946463
http://hdl.handle.net/20.500.12105/12915
The present work investigated the prevalence, spatial distribution, and temporal distribution of tuberculosis (TB) in free-ranging Eurasian badgers (Meles meles) and cattle in Asturias (Atlantic Spain) during a 13-year follow-up. The study objective was to assess the role of badgers as a TB reservoir for cattle and other sympatric wild species in the region. Between 2008 and 2020, 673 badgers (98 trapped and 575 killed in road traffic accidents) in Asturias were necropsied, and their tissue samples were cultured for the Mycobacterium tuberculosis complex (MTC) isolation. Serum samples were tested in an in-house indirect P22 ELISA to detect antibodies against the MTC. In parallel, data on MTC isolation and single intradermal tuberculin test results were extracted for cattle that were tested and culled as part of the Spanish National Program for the Eradication of Bovine TB. A total of 27/639 badgers (4.23%) were positive for MTC based on bacterial isolation, while 160/673 badgers (23.77%) were found to be positive with the P22 ELISA. The rate of seropositivity was higher among adult badgers than subadults. Badger TB status was spatially and temporally associated with cattle TB status. Our results cannot determine the direction of possible interspecies transmission, but they are consistent with the idea that the two hosts may exert infection pressure on each other. This study highlights the importance of the wildlife monitoring of infection and disease during epidemiological interventions in order to optimize outcomes.
eng
Atlantic Spain
Meles meles
Mycobacterium tuberculosis complex
P22 ELISA
Badger
Cattle
Isolation
Serology
Tuberculosis
Spatial and Temporal Distribution of Mycobacterium tuberculosis Complex Infection in Eurasian Badger (Meles meles) and Cattle in Asturias, Spain.
journal article
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