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oai:repisalud.isciii.es:20.500.12105/126762025-05-08T06:34:30Zcom_20.500.12105_2052com_20.500.12105_2051col_20.500.12105_19609

00925njm 22002777a 4500 dc Garcia-Gutiérrez, Carmen Alicia author Cuétara-García, María Soledad author Moragues, María Dolores author Ligero, Jorge author Quevedo, Sara Maria author Buitrago, Maria Jose author 2021-03-27 Although most bloodstream yeast infections are caused by Candida spp., infections by rare or less common species have increased in recent years. Diagnosis of infections caused by these species is difficult due to the lack of specific symptoms and adequate diagnostic tools. We describe two cases of fungemia by Rhodotorula mucilaginosa within a few months of each other, in a secondary Spanish hospital. In both cases, diagnosis was challenging. Blood subcultures in conventional fungal media were persistently negatives and the use of non-conventional fungal media was essential for isolating the yeasts and achieving a correct diagnosis. 1-3 beta-D-glucan detection and a panfungal PCR assay were helpful techniques to confirm the diagnosis CONCLUSION: It is highly important to establish an early diagnosis for fungemia. The process is challenging because often non-specific symptoms are presents. When yeasts grow in blood cultures other genera than Candida spp. could be the cause of infection. Patient risk factors should be assessed to incorporate alternative culture media and the available rapid diagnostic test, in order to provide an early recognition of the pathogen. Ann Clin Microbiol Antimicrob. 2021 Mar 27;20(1):21. http://hdl.handle.net/20.500.12105/12676 33773588 10.1186/s12941-021-00427-w 1476-0711 Annals of clinical microbiology and antimicrobials Fungemia Rhodotorula mucilaginosa Risk factors Specific culture media Low sensitivity of conventional fungal agars in fungemia by Rhodotorula mucilaginosa: description of two cases