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00925njm 22002777a 4500 dc Ruiz-de-León, María J author Jimenez-Sousa, Maria Angeles author Moreno, Santiago author García, Marcial author Gutiirrez-Rivas, Monica author León, Agathe author Montero-Alonso, Marta author González-García, Juan author Resino, Salvador author Rallón, Norma author Benito, José Miguel author Vallejo, Alejandro author ECRIS Network integrated in the Spanish AIDS Research Network author Briz, Veronica author Vázquez-Morón, Sonia author Fernández, A author García, P author Pernas, Maria author Casado, Concepcion author López, C author Capa, Laura author Pérez, M author Alcamí, José author 2019-08 Exosome-derived miR-21 was independently associated with CD4 T cell decline in HIV-1-infected elite controllers (OR 0.369, 95% CI 0.137-0.994, p = 0.049). Also, a negative correlation between miR-21 expression and MCP-1 level was found (r = -0.649, p = 0.020), while no correlation between soluble biomarkers or cellular immune activation was found. J Microbiol Immunol Infect . 2019 Aug;52(4):667-671. 10.1016/j.jmii.2018.07.007 1995-9133 Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi 30193823 http://hdl.handle.net/20.500.12105/12456 Exosomes miRNAs HIV-1 Elite controllers Immune activation Soluble biomarkers Lower expression of plasma-derived exosome miR-21 levels in HIV-1 elite controllers with decreasing CD4 T cell count