2026-07-05T14:53:21Zhttps://repisalud.isciii.es/rest/oai/requestoai:repisalud.isciii.es:20.500.12105/123282025-05-30T11:07:04Zcom_20.500.12105_2052com_20.500.12105_2051col_20.500.12105_19609
Repisalud
author
Wagner, L
author
Stielow, J B
author
de Hoog, G S
author
Bensch, K
author
Schwartze, V U
author
Voigt, K
author
Alastruey-Izquierdo, Ana
author
Kurzai, O
author
Walther, G
funder
Deutsche Forschungsgemeinschaft (Alemania)
funder
Federal Ministry for Health (Alemania)
funder
European Consortium of Microbial Resources Centres (EMbaRC)
funder
Unión Europea. Comisión Europea. 7 Programa Marco
funder
Federal Ministry of Education & Research (Alemania)
2021-03-16T18:37:06Z
2021-03-16T18:37:06Z
2020-06
Persoonia . 2020 Jun;44:67-97.
10.3767/persoonia.2020.44.03
0031-5850
Persoonia
33116336
http://hdl.handle.net/20.500.12105/12328
Mucor species are common soil fungi but also known as agents of human infections (mucormycosis) and used in food production and biotechnology. Mucor circinelloides is the Mucor species that is most frequently isolated from clinical sources. The taxonomy of Mucor circinelloides and its close relatives (Mucor circinelloides complex - MCC) is still based on morphology and mating behaviour. The aim of the present study was a revised taxonomy of the MCC using a polyphasic approach. Using a set of 100 strains molecular phylogenetic analysis of five markers (ITS, rpb1, tsr1, mcm7, and cfs, introduced here) were performed, combined with phenotypic studies, mating tests and the determination of the maximum growth temperatures. The multi-locus analyses revealed 16 phylogenetic species of which 14 showed distinct phenotypical traits and were recognised as discrete species. Five of these species are introduced as novel taxa: M. amethystinus sp. nov., M. atramentarius sp. nov., M. variicolumellatus sp. nov., M. pseudocircinelloides sp. nov., and M. pseudolusitanicus sp. nov. The former formae of M. circinelloides represent one or two separate species. In the MCC, the simple presence of well-shaped zygospores only indicates a close relation of both strains, but not necessarily conspecificity. Seven species of the MCC have been implemented in human infection: M. circinelloides, M. griseocyanus, M. janssenii, M. lusitanicus, M. ramosissimus, M. variicolumellatus, and M. velutinosus.
eng
Mucor
Mating tests
Maximum growth temperature
Mucormycosis
Mucormycosi
New taxa
Phylogeny
Taxonomy
Zygospore formation
A new species concept for the clinically relevant Mucor circinelloides complex
research article
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URL
https://repisalud.isciii.es/bitstreams/a6db144f-d57a-48c4-bce1-2890f9a214be/download
File
MD5
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application/pdf
ANewSpeciesConcept_2020.pdf
URL
https://repisalud.isciii.es/bitstreams/f00d8125-c53c-4137-ad5c-1f6287c8870c/download
File
MD5
978cc5d16c3b6481b8f12b8829bfd5dd
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text/plain
ANewSpeciesConcept_2020.pdf.txt