2026-06-14T05:05:43Zhttps://repisalud.isciii.es/rest/oai/requestoai:repisalud.isciii.es:20.500.12105/122852024-09-27T22:31:22Zcom_20.500.12105_2052com_20.500.12105_2051col_20.500.12105_19609
Repisalud
author
Marbán-Castro, Elena
author
Goncé, Anna
author
Fumadó, Victoria
author
Martínez, Miguel J
author
López, Marta
author
García-Otero, Laura
author
Salazar, Laura
author
Esteve, Carolina
author
Salvia, Dolors
author
Fortuny, Claudia
author
Eixarch, Elisenda
author
Fuente-Moreno, Marina
author
Pinazo, María Jesús
author
Oliveira, Inés
author
Rodríguez-Valero, Natalia
author
Requena-Méndez, Ana
author
Camprubí, Daniel
author
Saco, Adela
author
Castillo, Paola
author
Vazquez, Ana
author
De Ory, Fernando de
author
Navero-Castillejos, Jessica
author
Casellas, Aina
author
González, Raquel
author
Muñoz, José
author
Gascón, Joaquim
author
Ordi, Jaume
author
Menéndez, Clara
author
Bardají, Azucena
funder
Instituto de Salud Carlos III
funder
Ministerio de Ciencia, Innovación y Universidades (España)
funder
RETICS-Investigación colaborativa en Enfermedades Tropicales (RICET-ISCIII) (España)
funder
Unión Europea. Fondo Europeo de Desarrollo Regional (FEDER/ERDF)
funder
Government of Catalonia (España)
funder
Fundación La Caixa
2021-03-16T11:31:58Z
2021-03-16T11:31:58Z
2021-02-15
Travel Med Infect Dis . 2021 Feb 15;40:101985.
10.1016/j.tmaid.2021.101985
1873-0442
Travel medicine and infectious disease
33601028
http://hdl.handle.net/20.500.12105/12285
The emergence of Zika virus (ZIKV) represents a threat with consequences on maternal and children's health. We aimed to assess the clinical and epidemiological characteristics of pregnant women returning from ZIKV affected areas, and the effects of maternal ZIKV infection on birth outcomes and children's health.
This was a hospital-based prospective observational study conducted at the Hospital Clínic of Barcelona and Hospital Sant Joan de Déu, Barcelona, Spain, from January 2016 to February 2020.
One hundred and ninety-five pregnant women who had travelled to ZIKV affected areas during pregnancy were recruited. Four women (2.1%) had a confirmed ZIKV infection, 40 women (20.5%) a probable infection, and 151 (77.4%) were negative for ZIKV. Among the ZIKV confirmed cases, a pregnant woman suffered a miscarriage, highly plausible to be associated with ZIKV infection. Brain cysts and microcalcifications were detected in 7% of fetuses or infants from women with confirmed or probable ZIKV infection. Neurodevelopmental delay in the language function was found in 33.3% out of the 21 children evaluated.
These findings contribute to the understanding of ZIKV prevalence estimates, and the impact of maternal ZIKV infection on pregnancy outcomes and children's health. Results highlight the importance of long-term surveillance in pregnant travellers and their children.
eng
Zika virus
Pregnancy
Children
Fetal
Surveillance
Neurodevelopment
Zika virus infection in pregnant travellers and impact on childhood neurodevelopment in the first two years of life: A prospective observational study.
journal article
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