2026-06-14T02:29:17Zhttps://repisalud.isciii.es/rest/oai/requestoai:repisalud.isciii.es:20.500.12105/118392024-09-27T17:34:56Zcom_20.500.12105_2052com_20.500.12105_2051col_20.500.12105_19608
Repisalud
author
Iniesta-Marmol, Carlos
author
Coll, Pep
author
Barbera, Maria Jesus
author
García Deltoro, Miguel
author
Camino, Xabier
author
Fagúndez, Gabriela
author
Diaz Franco, Asuncion
author
Polo, Rosa
funder
National AIDS Programme
funder
Ministerio de Sanidad (España)
2021-02-10T13:31:17Z
2021-02-10T13:31:17Z
2021
PLoS One. 2021 Feb 8;16(2):e0246129.
10.1371/journal.pone.0246129
1932-6203
PloS one
33556085
http://hdl.handle.net/20.500.12105/11839
Pre-exposure prophylaxis (PrEP) is an effective and cost-effective strategy for HIV prevention. Spain carried out an implementation study in order to assess the feasibility of implementing PrEP programmes within its heterogeneous health system.
Observational longitudinal study conducted on four different types of health-care setting: a community centre (CC), a sexually transmitted infections clinic (STIC), a hospital-based HIV unit (HBHIVU) and a hospital-based STI unit (HBSTIU). We recruited gay, bisexual and other men who have sex with men (GBSM) and transgender women at risk of HIV infections, gave them PrEP and monitored clinical, behavioural PrEP-related and satisfaction information for 52 weeks. We collected perceptions on PrEP implementation feasibility from health-care professionals participating in the study.
A total of 321 participants were recruited, with 99.1% being GBMSM. Overall retention was 87.2% and it was highest at the CC (92.6%). Condom use decreased during the study period, while STIs did not increase consistently. The percentage of people who did not miss any doses of PrEP during the previous week remained at over 93%. No HIV seroconversions occurred. We observed overall decreases in GHB (32.5% to 21.8%), cocaine (27.5% to 21.4%), MDMA (25.7% to 14.3%), speed (11.4% to 5.7%) and mephedrone use (10.7% to 5.0%). The overall participant satisfaction with PrEP was 98.6%. Health-care professionals' perceptions of PrEP feasibility were positive, except for the lack of personnel.
PrEP implementation is feasible in four types of health-care settings. Local specificities have to be taken into consideration while implementing PrEP.
eng
Implementation of pre-exposure prophylaxis programme in Spain. Feasibility of four different delivery models.
journal article
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ImplementationOfPreExposureS1Appendix_2021.pdf.txt
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