2026-06-14T03:40:43Zhttps://repisalud.isciii.es/rest/oai/requestoai:repisalud.isciii.es:20.500.12105/117712025-04-24T05:48:02Zcom_20.500.12105_2052com_20.500.12105_2051col_20.500.12105_19609
Repisalud
author
Infantes-Lorenzo, Jose Antonio
author
Romero, B
author
Rodríguez-Bertos, A
author
Roy, A
author
Ortega, J
author
Juan Ferre, Lucia de
author
Moreno-Iruela, Inmaculada
author
Dominguez-Rodriguez, Mercedes
author
Domínguez, L
author
Bezos, J
funder
Ministerio de Economía, Industria y Competitividad (España)
funder
Unión Europea
2021-02-02T08:24:40Z
2021-02-02T08:24:40Z
2020-11-10
BMC Vet Res . 2020 Nov 10;16(1):435.
10.1186/s12917-020-02665-0
1746-6148
BMC veterinary research
33172453
http://hdl.handle.net/20.500.12105/11771
Background: Animal tuberculosis (TB) is distributed worldwide and has a wide range of wild and domestic reservoirs. Few studies concerning TB in camelids have been published in the last decade, particularly as regards Old World Camelids (OWC), but the increase in reports of TB outbreaks in these species in recent years suggests a high susceptibility to the infection. Case presentation: We studied a dromedary camel (Camelus dromedarius) herd (n = 24) in which a Mycobacterium caprae infection was detected. The TB infection was confirmed in one animal at necropsy through the detection of TB lesions, mainly in the abdominal organs, and the subsequent isolation of M. caprae (SB0157 spoligotype). The whole herd was additionally tested using cellular and humoral based diagnostic techniques. The intradermal tuberculin test results were compared with those obtained using P22 ELISA for the detection of specific antibodies against the M. tuberculosis complex. The TB infected animal was a positive reactor to both the intradermal tuberculin tests and P22 ELISA, while the others were negative to all the diagnostic tests. Conclusion: The present study found M. caprae infection in OWC. This is the first report of M. caprae infection in an OWC not living in a zoo. Since the animal was born in the herd and fed with goat's milk, this practice was suspected to be the potential source of TB infection, which was not confirmed in the other animals present in the herd. Moreover, our results highlight that the intradermal tuberculin test and the P22 ELISA could be valuable tools for the diagnosis of TB in OWC.
eng
Animal tuberculosis
Diagnostic tests
Mycobacterium caprae
Old World Camelids
Pathology
Tuberculosis caused by Mycobacterium caprae in a camel (Camelus dromedarius)
research article
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TuberculosisCausedByMycobacterium_2020.pdf
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TuberculosisCausedByMycobacterium_2020.pdf.txt