2026-07-22T20:10:58Zhttps://repisalud.isciii.es/rest/oai/requestoai:repisalud.isciii.es:20.500.12105/116802024-11-28T16:29:25Zcom_20.500.12105_2052com_20.500.12105_2051com_20.500.12105_15322col_20.500.12105_19609col_20.500.12105_16938
Repisalud
author
Sandonís, Virginia
author
Garcia-Rios, Estefani
author
McConnell, Michael J
author
Perez-Romero, Pilar
funder
Instituto de Salud Carlos III
funder
Ministerio de Ciencia, Innovación y Universidades (España)
funder
RETICS-Investigación en Patología Infecciosa (REIPI-ISCIII) (España)
funder
Unión Europea. Fondo Europeo de Desarrollo Regional (FEDER/ERDF)
2021-01-27T08:33:54Z
2021-01-27T08:33:54Z
2020-11
Trends Microbiol. 2020 Nov;28(11):900-912.
10.1016/j.tim.2020.04.003
1878-4380
Trends in microbiology
32448762
http://hdl.handle.net/20.500.12105/11680
Cytomegalovirus (CMV) infection elicits a potent immune response that includes the stimulation of antibodies with neutralizing activity. Recent studies have focused on elucidating the role of neutralizing antibodies in protecting against CMV infection and disease and characterizing viral antigens against which neutralizing antibodies are directed. Here, we provide a synthesis of recent data regarding the role of neutralizing antibodies in protection against CMV infection/disease. We consider the role of humoral immunity in the context of the global CMV-specific immune response, and the implications that recent findings have for vaccine and antibody-based therapy design.
eng
CMV-specific immune response
Antibody-based therapeutics
Cytomegalovirus
Neutralizing antibodies
Vaccine design
Role of Neutralizing Antibodies in CMV Infection: Implications for New Therapeutic Approaches
research article
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URL
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File
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RoleOfNeutralizingAntibodies_2020.pdf
URL
https://repisalud.isciii.es/bitstreams/e3f59731-a814-49e8-8959-b93fc2f883d0/download
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text/plain
RoleOfNeutralizingAntibodies_2020.pdf.txt