2026-06-30T04:06:47Zhttps://repisalud.isciii.es/rest/oai/request

oai:repisalud.isciii.es:20.500.12105/116432025-04-03T18:59:03Zcom_20.500.12105_2052com_20.500.12105_2051com_20.500.12105_15322col_20.500.12105_19609col_20.500.12105_16938col_20.500.12105_16970col_20.500.12105_16973col_20.500.12105_16978col_20.500.12105_16982

00925njm 22002777a 4500 dc Pérez-Nadales, Elena author Alastruey-Izquierdo, Ana author Linares-Sicilia, María José author Soto-Debran, Juan Carlos author Abdala, Edson author García-Rodríguez, Julio author Montejo, Miguel author Muñoz, Patricia author Salavert Lletí, Miguel author Rezusta, Antonio author Ruiz Pérez de Pipaón, Maite author Yáñez, Lucrecia author Merino, Esperanza author Campos-Herrero, María Isolina author Costa-Mateo, José María author Fortún, Jesús author García-Lozano, Tomás author Garcia-Vidal, Carolina author Fernández-Ruiz, Mario author Sánchez-Reus, Ferran author Castro-Méndez, Carmen author Guerrero-Lozano, Inmaculada author Soler-Palacín, Pere author Aguado, José María author Martínez-Martínez, Luis author Torre-Cisneros, Julian author Nucci, Marcio author 2021-01 Invasive fusariosis (IF) is associated with severe neutropenia in patients with concurrent hematologic conditions. We conducted a retrospective observational study to characterize the epidemiology of IF in 18 Spanish hospitals during 2000-2015. In that time, the frequency of IF in nonneutropenic patients increased from 0.08 cases per 100,000 admissions in 2000-2009 to 0.22 cases per 100,000 admissions in 2010-2015. Nonneutropenic IF patients often had nonhematologic conditions, such as chronic cardiac or lung disease, rheumatoid arthritis, history of solid organ transplantation, or localized fusariosis. The 90-day death rate among nonneutropenic patients (28.6%) and patients with resolved neutropenia (38.1%) was similar. However, the death rate among patients with persistent neutropenia (91.3%) was significantly higher. We used a multivariate Cox regression analysis to characterize risk factors for death: persistent neutropenia was the only risk factor for death, regardless of antifungal therapy. Emerg Infect Dis . 2021 Jan;27(1):26-35 10.3201/eid2701.190782 1080-6059 Emerging infectious diseases 33352085 http://hdl.handle.net/20.500.12105/11643 Invasive Fusariosis in Nonneutropenic Patients, Spain, 2000-2015.