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oai:repisalud.isciii.es:20.500.12105/116402024-09-27T22:22:42Zcom_20.500.12105_2052com_20.500.12105_2051col_20.500.12105_19609

00925njm 22002777a 4500 dc Calvo-Cano, Antonia author Garduño-Eseverri, Eugenio author Alastruey-Izquierdo, Ana author Hernández-Gallego, Román author Martínez-Gallardo, Rocío author Rodríguez-Vidigal, Francisco Félix author 2020-12 Invasive aspergillosis (IA) is associated with a high mortality rate in kidney-transplant recipients. Azole-resistance is increasing in Aspergillus fumigatus. We report a clinical case of a kidney-transplant recipient with cerebellar and pulmonary aspergillosis caused by azole-resistant Aspergillus parafelis (molecular identification through β-tubulin sequence). The patient experienced an effective resolution after three surgical procedures and associated antifungal therapy. This case highlights that azole-resistant aspergillosis should be considered in every patient with IA as long as susceptibility testing results are not known. Therefore, in selected patients with IA and central nervous system involvement, empirical combination antifungal therapy could be considered. Med Mycol Case Rep . 2020 Oct 17;30:35-38. 10.1016/j.mmcr.2020.10.001 2211-7539 Medical mycology case reports 33117642 http://hdl.handle.net/20.500.12105/11640 Aspergillus Aspergillus parafelis Invasive aspergillosis Kidney transplant Azole-resistant aspergillosis Successful treatment of invasive aspergillosis caused by Aspergillus parafelis in a kidney transplant recipient.