2026-06-14T03:46:57Zhttps://repisalud.isciii.es/rest/oai/request

oai:repisalud.isciii.es:20.500.12105/116142025-04-29T13:56:59Zcom_20.500.12105_2052com_20.500.12105_2051col_20.500.12105_19609

00925njm 22002777a 4500 dc Bermejo-Martin, Jesús F author Kelvin, David J author Guan, Yi author Chen, Honglin author Perez-Breña, Pilar author Casas Flecha, Inmaculada author Arranz, Eduardo author Ortíz de Lejarazu, Raúl author 2007-06 We have read with great interest the work of Sandbulte et al. recently published in your journal [1]. In this article, the authors provide evidence for the existence of cross-immunity between the neuraminidase of H5N1 viruses and that of endemic human H1N1 viruses. Age may be an important determining factor in the development of cross-immunity: younger people, having a shorter history of H1N1 exposure, may be disproportionately susceptible to H5N1 infection. PLoS Med . 2007 Jun;4(6):e212. d 10.1371/journal.pmed.0040212 1549-1676 PLoS medicine 17593897 http://hdl.handle.net/20.500.12105/11614 Neuraminidase antibodies and H5N1: geographic-dependent influenza epidemiology could determine cross-protection against emerging strains