2026-06-14T03:40:22Zhttps://repisalud.isciii.es/rest/oai/requestoai:repisalud.isciii.es:20.500.12105/115882025-05-20T08:41:51Zcom_20.500.12105_2052com_20.500.12105_2051com_20.500.12105_19604com_20.500.12105_15322col_20.500.12105_19613col_20.500.12105_19605col_20.500.12105_16977
Repisalud
author
Roth, Gregory A
author
Mensah, George A
author
Johnson, Catherine Owens
author
Addolorato, Giovanni
author
Ammirati, Enrico
author
Baddour, Larry M
author
Barengo, Noël C
author
Beaton, Andrea Z
author
Benjamin, Emelia J
author
Benziger, Catherine P
author
Bonny, Aimé
author
Brauer, Michael
author
Brodmann, Marianne
author
Cahill, Thomas J
author
Carapetis, Jonathan
author
Catapano, Alberico
author
Chugh, Sumeet S
author
Cooper, Leslie T
author
Coresh, Josef
author
Criqui, Michael
author
DeCleene, Nicole
author
Eagle, Kim A
author
Emmons-Bell, Sophia
author
Feigin, Valery L
author
Fernandez-Sola, Joaquim
author
Fowkes, Gerry
author
Gakidou, Emmanuela
author
Grundy, Scott M
author
He, Feng J
author
Howard, George
author
Hu, Frank
author
Inker, Lesley
author
Karthikeyan, Ganesan
author
Kassebaum, Nicholas
author
Koroshetz, Walter
author
Lavie, Carl
author
Lloyd-Jones, Donald
author
Lu, Hong S
author
Mirijello, Antonio
author
Temesgen, Awoke Misganaw
author
Mokdad, Ali H
author
Moran, Andrew E
author
Muntner, Paul
author
Narula, Jagat
author
Neal, Bruce
author
Ntsekhe, Mpiko
author
Moraes de Oliveira, Glaucia
author
Otto, Catherine
author
Owolabi, Mayowa Ojo
author
Pratt, Michael
author
Rajagopalan, Sanjay
author
Reitsma, Marissa
author
Ribeiro, Antonio Luiz P
author
Rigotti, Nancy
author
Rodgers, Anthony
author
Sable, Craig
author
Shakil, Saate
author
Sliwa-Hahnle, Karen
author
Stark, Benjamin
author
Sundström, Johan
author
Timpel, Patrick
author
Tleyjeh, Imad M
author
Valgimigli, Marco
author
Vos, Theo
author
Whelton, Paul K
author
Yacoub, Magdi
author
Zuhlke, Liesl
author
Murray, Christopher J L
author
Fuster, Valentin
author
GBD-NHLBI-JACC
Global Burden of Cardiovascular Diseases Writing Group
author
Catalá-López, Ferrán
funder
Aegerion Pharmaceuticals (Estados Unidos)
funder
Akcea Therapeutics
funder
American Heart Association
funder
Amgen
funder
Amryt Pharma
funder
AstraZeneca
funder
Bill & Melinda Gates Foundation
funder
National Council for Scientific and Technological Development (Brasil)
funder
Daiichi Sankyo
funder
Eli Lilly
funder
Unión Europea. Comisión Europea. H2020. ERA-NET
funder
Esperion Therapeutics (Estados Unidos)
funder
Fundação de Amparo à Pesquisa do Estado de São Paulo Minas Gerais (Brasil)
funder
Fondazione Cariplo
funder
George Medicines Pty Ltd (GM)
funder
Unión Europea. Comisión Europea. H2020
funder
Ionis Pharmaceuticals
funder
Kowa (Japón)
funder
Grupo Menarini
funder
Merck KGaA
funder
Ministry of Health - Ricerca Corrente Multimedica
funder
Mylan
funder
NIH - National Heart, Lung, and Blood Institute (NHLBI) (Estados Unidos)
funder
National Kidney Foundation (Estados Unidos)
funder
National Institutes of Health (Estados Unidos)
funder
Novartis
funder
Recordati
funder
Regeneron (Estados Unidos)
funder
Sandoz Farmacéutica
funder
Sanofi
funder
George Institute for Global Health
funder
Department for International Development (Reino Unido)
funder
Medical Research Council (Reino Unido)
funder
UpToDate, Inc.
2021-01-08T10:29:43Z
2021-01-08T10:29:43Z
2020-12-22
J Am Coll Cardiol. 2020; 76(25):2982-3021
10.1016/j.jacc.2020.11.010
1558-3597
0735-1097
Journal of the American College of Cardiology
33309175
http://hdl.handle.net/20.500.12105/11588
Cardiovascular diseases (CVDs), principally ischemic heart disease (IHD) and stroke, are the leading cause of global mortality and a major contributor to disability. This paper reviews the magnitude of total CVD burden, including 13 underlying causes of cardiovascular death and 9 related risk factors, using estimates from the Global Burden of Disease (GBD) Study 2019. GBD, an ongoing multinational collaboration to provide comparable and consistent estimates of population health over time, used all available population-level data sources on incidence, prevalence, case fatality, mortality, and health risks to produce estimates for 204 countries and territories from 1990 to 2019. Prevalent cases of total CVD nearly doubled from 271 million (95% uncertainty interval [UI]: 257 to 285 million) in 1990 to 523 million (95% UI: 497 to 550 million) in 2019, and the number of CVD deaths steadily increased from 12.1 million (95% UI:11.4 to 12.6 million) in 1990, reaching 18.6 million (95% UI: 17.1 to 19.7 million) in 2019. The global trends for disability-adjusted life years (DALYs) and years of life lost also increased significantly, and years lived with disability doubled from 17.7 million (95% UI: 12.9 to 22.5 million) to 34.4 million (95% UI:24.9 to 43.6 million) over that period. The total number of DALYs due to IHD has risen steadily since 1990, reaching 182 million (95% UI: 170 to 194 million) DALYs, 9.14 million (95% UI: 8.40 to 9.74 million) deaths in the year 2019, and 197 million (95% UI: 178 to 220 million) prevalent cases of IHD in 2019. The total number of DALYs due to stroke has risen steadily since 1990, reaching 143 million (95% UI: 133 to 153 million) DALYs, 6.55 million (95% UI: 6.00 to 7.02 million) deaths in the year 2019, and 101 million (95% UI: 93.2 to 111 million) prevalent cases of stroke in 2019. Cardiovascular diseases remain the leading cause of disease burden in the world. CVD burden continues its decades-long rise for almost all countries outside high-income countries, and alarmingly, the age-standardized rate of CVD has begun to rise in some locations where it was previously declining in high-income countries. There is an urgent need to focus on implementing existing cost-effective policies and interventions if the world is to meet the targets for Sustainable Development Goal 3 and achieve a 30% reduction in premature mortality due to noncommunicable diseases.
eng
Global Burden of Cardiovascular Diseases and Risk Factors, 1990-2019: Update From the GBD 2019 Study.
research article
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