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oai:repisalud.isciii.es:20.500.12105/115242025-06-09T10:10:19Zcom_20.500.12105_2052com_20.500.12105_2051col_20.500.12105_19609

00925njm 22002777a 4500 dc Trallero, Gloria author Casas Flecha, Inmaculada author Tenorio, Antonio author Echevarria, Juan Emilio author Castellanos-Nadal, Ana Maria author Lozano, Alvaro author Perez-Breña, Pilar author 2000-06 A total of 15,662 clinical samples were analysed for enterovirus (EV) isolation in cell cultures during a 10-year period (1988-97). Furthermore, 210 isolates of EV obtained in primary laboratories within Spain from patients with meningitis were characterized. The total number of EV typed was 758, including 727 non-polio EV and 31 Sabin-like (SL) polioviruses. Twenty-eight EV serotypes were represented. Echoviruses comprised 90% (653/727) of fully typed non-polio EV. The four most prevalent serotypes were echovirus 30, echovirus 9, echovirus 6 and echovirus 4. Echovirus 30 was the main serotype associated with meningitis. Echovirus 9 was the aetiological agent in 20 outbreaks of meningitis while the occurrence of echovirus 6 was localized in 1 year (1997). Coxsackieviruses A and B occurred in 3 and 7% of the non-polio EV respectively. Coxsackievirus B5 presented the relative greater abundance. This paper examines the epidemiology of EV in Spain to serotype level over a 10-year period with special attention to non-polio EV associated with meningitis. Epidemiol Infect 2000 Jun;124(3):497-506. 10.1017/s0950268899003726 1469-4409 Epidemiology and infection https://pmc.ncbi.nlm.nih.gov/articles/PMC2810936/pdf/10982074.pdf 10982074 http://hdl.handle.net/20.500.12105/11524 Enteroviruses in Spain: virological and epidemiological studies over 10 years (1988-97)