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00925njm 22002777a 4500 dc Cabrerizo, Maria author De Miguel, T author Armada, A author Martínez-Risco, R author Pousa Ortega, Ánxela author Trallero, Gloria author 2010-12 Few reports exist regarding the association between onychomadesis and an enterovirus infection presenting clinically as hand, foot, and mouth disease (HFMD). In February 2009, an outbreak of HFMD occurred in a Spanish nursery school, followed by onychomadesis 36-69 days later. Twelve of 17 children with HFMD developed nail shedding; enterovirus was detected in stool samples from eight (47%) of the 17. However, in only three of the children could an enterovirus serotype coxsackievirus B1 be identified. The epidemiological results of this study confirm onychomadesis as a complication in HFMD. In future outbreaks, molecular characterization of enterovirus from appropriate clinical samples should be studied. Epidemiol Infect . 2010 Dec;138(12):1775-8. 10.1017/S0950268810002219 0950-2688 Epidemiology and infection 20854714 http://hdl.handle.net/20.500.12105/11499 Onychomadesis after a hand, foot, and mouth disease outbreak in Spain, 2009.