2026-04-29T22:57:51Zhttps://repisalud.isciii.es/rest/oai/requestoai:repisalud.isciii.es:20.500.12105/114932024-09-27T22:11:54Zcom_20.500.12105_2052com_20.500.12105_2051col_20.500.12105_19609
Repisalud
author
Fernández-Natal, I
author
Saez-Nieto, Juan Antonio
author
Medina-Pascual, Maria Jose
author
Albersmeier, A
author
Valdezate, Sylvia
author
Guerra-Laso, J M
author
Rodríguez, H
author
Marrodán, T
author
Parras, T
author
Tauch, A
author
Soriano, F
funder
Junta de Castilla y León (España)
2020-12-03T08:42:35Z
2020-12-03T08:42:35Z
2013-12
New Microbes New Infect . 2013 Dec;1(3):35-40.
10.1002/2052-2975.31
2052-2975
New microbes and new infections
25356327
http://hdl.handle.net/20.500.12105/11493
During a 12-year period, Dermabacter hominis was isolated from 21 clinical samples belonging to 14 patients attending a tertiary hospital in León, Spain. Samples included blood cultures (14), peritoneal dialysis catheter exit sites (three), cutaneous abscesses (two), an infected vascular catheter (one) and a wound swab (one). Identification was made by API Coryne™ V2.0, Biolog™ GP2 and 16S rRNA gene amplification. Six febrile patients had positive blood cultures (one, two or three sets) and all of them were treated with teicoplanin (two patients), vancomycin, ampicillin plus gentamicin, amoxicillin/clavulanic acid and ciprofloxacin (one each). An additional patient with a single positive blood culture was not treated, the finding being considered non-significant. In the remaining seven patients the organism was isolated from a single specimen and three of them received antimicrobial treatment (ciprofloxacin, ceftriaxone plus vancomycin and amoxicillin/clavulanic acid). At least ten patients had several underlying diseases and conditions, and no direct mortality was observed in relation to the isolated organism. All isolates were susceptible to vancomycin, rifampin and linezolid. Resistance to other antibiotics varied: erythromycin (100%), clindamycin (78.5%), ciprofloxacin (21.4%) and gentamicin, quinupristin-dalfopristin, benzylpenicillin and imipenem 7.1% each. Thirteen isolates were highly resistant to daptomycin with MICs ranging from 8 to 48 (MIC90 = 32 mg/L); only one was daptomycin-sensitive (MIC = 0.19 mg/L).
eng
Antimicrobial susceptibility
Dermabacter hominis
Clinical relevance
Daptomycin resistance
Identification
Isolation
Dermabacter hominis: a usually daptomycin-resistant gram-positive organism infrequently isolated from human clinical samples.
journal article
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DermabacterHominisAUsually_2013.pdf
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DermabacterHominisAUsually_2013.pdf.txt