2026-04-29T04:10:21Zhttps://repisalud.isciii.es/rest/oai/request

oai:repisalud.isciii.es:20.500.12105/114922024-09-28T00:00:17Zcom_20.500.12105_2052com_20.500.12105_2051col_20.500.12105_19609

00925njm 22002777a 4500 dc Fernández-Natal, I author Saez-Nieto, Juan Antonio author Rodríguez-Lázaro, David author Valdezate, Sylvia author Parras-Padilla, T author Medina-Pascual, Maria Jose author Rodríguez-Pollán, R H author Blom, J author Tauch, A author Soriano, F author 2016-03 During a 12-year period we isolated five Corynebacterium argentoratense strains identified by phenotypic methods, including the use of matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF) and 16S rRNA gene sequencing. In addition, antimicrobial susceptibility was determined, and genome sequencing for the detection of antibiotic resistance genes was performed. The organisms were isolated from blood and throat cultures and could be identified by all methods used. All strains were resistant to cotrimoxazole, and resistance to β-lactams was partly present. Two strains were resistant to erythromycin and clindamycin. The draft genome sequences of theses isolates revealed the presence of the erm(X) resistance gene that is embedded in the genetic structure of the transposable element Tn5423. Although rarely reported as a human pathogen, C. argentoratense can be involved in bacteraemia and probably in other infections. Our results also show that horizontal transfer of genes responsible for antibiotic resistance is occurring in this species. New Microbes New Infect . 2016 Jan 22;10:116-21. http://hdl.handle.net/20.500.12105/11492 26933505 10.1016/j.nmni.2016.01.007 2052-2975 New microbes and new infections Antimicrobial resistance Corynebacterium argentoratense MALDI-TOF Clinical infections Whole genome sequencing Phenotypic, molecular characterization, antimicrobial susceptibility and draft genome sequence of Corynebacterium argentoratense strains isolated from clinical samples.