2026-06-14T03:51:47Zhttps://repisalud.isciii.es/rest/oai/requestoai:repisalud.isciii.es:20.500.12105/114262024-09-27T23:31:13Zcom_20.500.12105_2052com_20.500.12105_2051col_20.500.12105_19609
Repisalud
author
Álvaro-Meca, Alejandro
author
Sánchez-Lopez, Ainhoa
author
Resino, Rosa
author
Tamayo, Eduardo
author
Resino, Salvador
funder
Instituto de Salud Carlos III
funder
Junta de Castilla y León (España)
2020-11-25T10:59:39Z
2020-11-25T10:59:39Z
2020-08-27
Environ Res. 2020 Dec;191:110102.
10.1016/j.envres.2020.110102
1096-0953
Environmental research
32861723
http://hdl.handle.net/20.500.12105/11426
Objective: Pneumonia is a common cause of morbidity and sepsis worldwide, mainly in the elderly. We evaluated the impact of short-term exposure to environmental factors on hospital admissions for sepsis-related pneumonia in a nationwide study in Spain. Methods: We conducted a bidirectional case-crossover study in patients who had sepsis-related pneumonia in 2013. Data were obtained from the Minimum Basic Data Set (MBDS) and the State Meteorological Agency (AEMET) of Spain. Conditional logistic regressions were used to evaluate the association between environmental factors (temperature, relative humidity, NO2, SO2, O3, PM10, and CO) and hospital admissions with sepsis-related pneumonia. Results: A total of 3,262,758 hospital admissions were recorded in the MBDS, of which, 253,467 were patients with sepsis. Among those, 67,443 had sepsis-related pneumonia and zip code information. We found inverse associations [adjusted odds ratio (aOR) values < 1] between short-term exposure to temperature and hospital admissions for sepsis-related pneumonia. Moreover, short-term exposure to higher levels of relative humidity, NO2, SO2, O3, PM10, and CO were directly associated (aOR values > 1) with a higher risk of hospital admissions for sepsis-related pneumonia. Overall, the impact of environmental factors was more prominent with increasing age, mainly among the elderly aged 65 or over. Conclusion: Short-term exposure to environmental factors (temperature, relative humidity, NO2, SO2, O3, CO, and PM10) was associated with a higher risk of hospital admissions for sepsis-related pneumonia. Our findings support the role of environmental factors in monitoring the risk of hospital admissions for sepsis-related pneumonia and can help plan and prepare public health resources.
eng
Age
Environment
ICD-9-CM
Pneumonia
Sepsis
Environmental factors are associated with hospital admissions for sepsis-related pneumonia: A bidirectional case-crossover design
research article
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https://repisalud.isciii.es/bitstreams/b0137e52-52ed-447e-8b5b-30f4367ec64d/download
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application/pdf
EnvironmentalFactorsAreAssociated_2020.pdf
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https://repisalud.isciii.es/bitstreams/fc3de882-021a-4fe8-af34-1b639a9aa9f3/download
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text/plain
EnvironmentalFactorsAreAssociated_2020.pdf.txt