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00925njm 22002777a 4500 dc Aran, Begoña author Lukovic, Dunja author Aguilar-Quesada, Rocio author Veiga, Anna author 2020 The Spanish National Stem Cell Bank (Banco Nacional de Líneas Celulares, BNLC) was established in 2006 thanks to a change in the legislative framework in Spain. The Law 14/2006 updated the previous Assisted Reproduction Techniques Law (Law 45/2003) allowing the use of the surplus frozen embryos following IVF for research. The BNLC has a network structure with 3 nodes: the Regenerative Medicine Program (IDIBELL), the Principe Felipe Research Center (CIPF) in Valencia and the Andalusian Public Health System Biobank (SSPA Biobank) in Granada. The aim of the BNLC is to guarantee throughout the national territory the availability of human stem cell lines for biomedical research. At present time, there are 40 human embryonic stem cell lines (hESC) and 171 human induced pluripotent stem cell lines (hiPSC) registered in the BNLC. These lines are fully characterized and available in the context of research projects approved by the Technical Committee of the BNLC. Stem Cell Res . 2020 Oct;48:101956. 10.1016/j.scr.2020.101956 1873-5061 Stem cell research 32905997 http://hdl.handle.net/20.500.12105/11408 Pluripotent stem cell regulation in Spain and the Spanish National Stem Cell Bank.