2026-08-29T16:26:13Zhttps://repisalud.isciii.es/rest/oai/requestoai:repisalud.isciii.es:20.500.12105/112092024-09-27T08:45:25Zcom_20.500.12105_19604com_20.500.12105_2051col_20.500.12105_19605
Repisalud
author
Fuertes, Teresa
author
Ramiro, Almudena R
author
de Yebenes, Virginia G
funder
Ministerio de Ciencia, Innovación y Universidades (España)
funder
Centro Nacional de Investigaciones Cardiovasculares Carlos III (España)
funder
Complutense University of Madrid (España)
funder
Instituto de Salud Carlos III
funder
Fundación ProCNIC
2020-10-27T13:49:14Z
2020-10-27T13:49:14Z
2020-10
Trends Immunol. 2020; 41(10):932-947
10.1016/j.it.2020.08.006
1471-4906
Trends in immunology
32888820
http://hdl.handle.net/20.500.12105/11209
Non-Hodgkin lymphoma (NHL) is a diverse class of hematological cancers, many of which arise from germinal center (GC)-experienced B cells. Thus GCs, the sites of antibody affinity maturation triggered during immune responses, also provide an environment that facilitates B cell oncogenic transformation. miRNAs provide attractive and mechanistically different strategies to treat these malignancies based on their potential for simultaneous modulation of multiple targets. Here, we discuss the scientific rationale for miRNA-based therapeutics in B cell neoplasias and review recent advances that may help establish a basis for novel candidate miRNA-based therapies for B cell-NHL (B-NHL).
eng
miRNA-Based Therapies in B Cell Non-Hodgkin Lymphoma.
journal article
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URL
https://repisalud.isciii.es/bitstreams/b13070f4-0045-4e38-ae9f-f5280efccbed/download
File
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application/pdf
miRNA-BasedTherapiesBCell_2020.pdf
URL
https://repisalud.isciii.es/bitstreams/7be0f6f1-159b-4ac8-a300-026979fb999c/download
File
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miRNA-BasedTherapiesBCell_2020.pdf.txt