2026-04-28T22:57:08Zhttps://repisalud.isciii.es/rest/oai/requestoai:repisalud.isciii.es:20.500.12105/111362024-09-27T08:22:55Zcom_20.500.12105_19604com_20.500.12105_2051col_20.500.12105_19605
Repisalud
author
Laveriano-Santos, Emily P.
author
Parilli-Moser, Isabella
author
Ramírez-Garza, Sonia L.
author
Tresserra-Rimbau, Anna
author
Storniolo, Carolina E.
author
Ruiz-León, Ana María
author
Estruch, Ramón
author
Bodega, Patricia
author
de Miguel, Mercedes
author
de Cos-Gandoy, Amaya
author
Carral, Vanesa
author
Santos-Beneit, Gloria
author
Fernandez-Alvira, Juan Miguel
author
Fernandez-Jimenez, Rodrigo
author
Fuster, Valentin
author
Lamuela-Raventós, Rosa María
funder
Fundación SHE
funder
Fundación La Caixa
funder
Fundación La Marató TV3
funder
Instituto de Salud Carlos III
funder
Unión Europea
funder
Ministerio de Ciencia, Innovación y Universidades (España)
funder
Government of Catalonia (España)
funder
Fundación ProCNIC
2020-10-09T07:42:27Z
2020-10-09T07:42:27Z
2020-09
Antioxidants (Basel). 2020; 9(10):910
http://hdl.handle.net/20.500.12105/11136
10.3390/antiox9100910
2076-3921
Antioxidants
Background: Epidemiological studies have shown an inverse association between polyphenol intake and cardiovascular risk factors (CVRFs) in adults, but few have provided information about adolescents. The aim of this study was to evaluate the relationship between urinary total polyphenol excretion (TPE) and CVRFs in adolescents. (2) Methods: A cross-sectional study was performed in 1194 Spanish adolescents from the SI! (Salud Integral) program. TPE in urine samples was determined by the Folin–Ciocalteu method, after solid-phase extraction, and categorized into quartiles. The association between TPE and CVRFs was estimated using mixed-effect linear regression and a structural equation model (SEM). (3) Results: Linear regression showed negative associations among the highest quartile of TPE and body fat percentage (B = −1.75, p-value = <0.001), triglycerides (TG) (B = −17.68, p-value = <0.001), total cholesterol (TC) (B = −8.66, p-value = 0.002), and low-density lipoprotein (LDL)-cholesterol (LDL-C) (B = −4.09, p-value = 0.008) in boys, after adjusting for all confounder variables. Negative associations between TPE quartiles and systolic blood pressure (SBP), diastolic blood pressure (DBP), and were also found in girls. Moreover, a structural equation model revealed that TPE was directly associated with body composition and blood glucose and indirectly associated with blood pressure, TG, LDL-C, and high-density lipoprotein-cholesterol (HDL-C) in boys. (4) Conclusions: Higher concentrations of TPE were associated with a better profile of cardiovascular health, especially in boys, while in girls, the association was not as strong.
eng
Antioxidants
Pediatric
Body composition
Cardiovascular
Lipid profile
Folin-Ciocalteu
Polyphenols in Urine and Cardiovascular Risk Factors: A Cross-Sectional Analysis Reveals Gender Differences in Spanish Adolescents from the SI! Program
journal article
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PolyphenolsUrineCardiovascularRisk_2020.pdf
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PolyphenolsUrineCardiovascularRisk_2020.pdf.txt