2026-06-30T03:57:07Zhttps://repisalud.isciii.es/rest/oai/request

oai:repisalud.isciii.es:20.500.12105/108652025-04-04T09:36:36Zcom_20.500.12105_2052com_20.500.12105_2051com_20.500.12105_15322col_20.500.12105_19609col_20.500.12105_16938col_20.500.12105_16987

00925njm 22002777a 4500 dc Soriano-Arandes, Antoni author Frick, Marie Antoinette author García López-Hortelano, Milagros author Sulleiro, Elena author Rodó, Carlota author Cabrera-Lafuente, Marta author Suy, Anna author de la Calle, María author Santos, Mar author Antolin, Eugenia author Viñuela, María Del Carmen author Espiau, María author Salazar, Ainara author Guarch-Ibáñez, Borja author Navarro-Morón, Juan author Ramos-Amador, José-Tomás author Martin-Nalda, Andrea author Dueñas, Eva author Blázquez-Gamero, Daniel author Reques-Cosme, Resurrección author Olabarrieta, Iciar author Prieto, Luis author Thorne, Claire author Byrne, Thomas author Ades, Anthony E author Ruiz-Burga, Elisa author Giaquinto, Carlo author Mellado-Peña, María José author García-Alix, Alfredo author Carreras, Elena author Soler-Palacín, Pere author Sanchez, Marina P author Vazquez, Ana author De Ory, Fernando de author 2020-05-07 Zika virus (ZIKV) infection has been associated with congenital microcephaly and other neurodevelopmental abnormalities. There is little published research on the effect of maternal ZIKV infection in a non-endemic European region. We aimed to describe the outcomes of pregnant travelers diagnosed as ZIKV-infected in Spain, and their exposed children. This prospective observational cohort study of nine referral hospitals enrolled pregnant women (PW) who travelled to endemic areas during their pregnancy or the two previous months, or those whose sexual partners visited endemic areas in the previous 6 months. Infants of ZIKV-infected mothers were followed for about two years. ZIKV infection was diagnosed in 163 PW; 112 (70%) were asymptomatic and 24 (14.7%) were confirmed cases. Among 143 infants, 14 (9.8%) had adverse outcomes during follow-up; three had a congenital Zika syndrome (CZS), and 11 other potential Zika-related outcomes. The overall incidence of CZS was 2.1% (95%CI: 0.4-6.0%), but among infants born to ZIKV-confirmed mothers, this increased to 15.8% (95%CI: 3.4-39.6%). A nearly 10% overall risk of neurologic and hearing adverse outcomes was found in ZIKV-exposed children born to a ZIKV-infected traveler PW. Longer-term follow-up of these children is needed to assess whether there are any later-onset manifestations. Pathogens. 2020 May 7;9(5):352. 10.3390/pathogens9050352 2076-0817 Pathogens (Basel, Switzerland) 32392815 http://hdl.handle.net/20.500.12105/10865 Clinical Outcomes of a Zika Virus Mother-Child Pair Cohort in Spain