2026-05-17T05:52:20Zhttps://repisalud.isciii.es/rest/oai/request

oai:repisalud.isciii.es:20.500.12105/100932025-05-12T10:38:26Zcom_20.500.12105_2052com_20.500.12105_2051col_20.500.12105_19610

00925njm 22002777a 4500 dc Bartolome, Monica author Gallego-Picó, Alejandrina author Cutanda, Francisco author Huetos, Olga author Esteban-Lopez, Marta author Perez-Gomez, Beatriz author Castaño, Argelia author 2017-12-15 Per- and polyfluoroalkyl substances (PFAS) are widely found in humans and the environment. Their persistence, bioaccumulation and toxicity make them a source of increasing public health concern. In this study, we analyzed the concentrations and geographical distribution of six PFAS in the serum of 755 Spanish adults aged 18-65. The geometric mean concentrations (and P95 values) for PFOS (perfluoroctane sulfonate), PFOA (perfluorooctanoic acid), PFHxS (perfluorohexane sulfonate), PFNA (perfluorononanoic acid) and PFDA (perfluorodecanoic acid) were 7.67 (19.3), 1.99 (5.48), 0.91 (2.84), 0.96 (2.44) and 0.42 (0.99) μg/L, respectively. N-Methylperfluorooctane sulfonamide (N-MeFOSAA) was detected in only 3.3% of samples. Residents in northeast (Catalonia) and northwest of Spain (Galicia) were found to have the highest serum values, whereas residents in the Canary Islands had the lowest values for almost all PFAS. Men presented higher levels than women, and we confirm that lactation (breastfeeding) contributes to a reduced body burden for all PFAS in women. Our data provide new information on exposure to PFAS in a national cross section sample of Spanish adults, thus providing a proxy for reference values for the Spanish population and forming the base for following temporal trends in the future. Sci Total Environ. 2017 Dec 15;603-604:352-360. 10.1016/j.scitotenv.2017.06.031 1879-1026 00489697 The Science of the total environment 28633112 http://hdl.handle.net/20.500.12105/10093 Exposure Spanish adults Human biomonitoring Human serum samples PFOA PFOS Perfluorinated alkyl substances Perfluorinated alkyl substances in Spanish adults: Geographical distribution and determinants of exposure