TY - GEN AU - Valderrama-Carvajal, Alejandra AU - Irizar, Haritz AU - Gago, Belén AU - Jiménez-Urbieta, Haritz AU - Fuxe, Kjell AU - Rodríguez-Oroz, María C AU - Otaegui, David AU - Rivera, Alicia PY - 2018 DO - 10.1038/s41598-018-25604-4 UR - http://hdl.handle.net/20.500.12105/17595 AB - Morphine binding to opioid receptors, mainly to μ opioid receptor (MOR), induces alterations in intracellular pathways essential to the initial development of addiction. The activation of the dopamine D4 receptor (D4R), which is expressed in the... LA - eng KW - Analgesics, Opioid KW - Animals KW - Benzamides KW - Caudate Nucleus KW - Dopamine Agonists KW - Gene Expression KW - Male KW - Morphine KW - Piperazines KW - Putamen KW - Rats KW - Rats, Sprague-Dawley KW - Receptors, Dopamine D4 KW - Receptors, Opioid, mu KW - Signal Transduction KW - Transcriptome TI - Transcriptomic integration of D4R and MOR signaling in the rat caudate putamen. TY - research article ER -