TY  - JOUR
AU  - Lopez, Sophie
AU  - Voisset, Edwige
AU  - Tisserand, Julie C
AU  - Mosca, Cyndie
AU  - Prebet, Thomas
AU  - Santamaria, David
AU  - Dubreuil, Patrice
AU  - De Sepulveda, Paulo
PY  - 2016
DO  - 10.18632/oncotarget.9965
SN  - 1949-2553
UR  - http://hdl.handle.net/20.500.12105/8876
AB  - CDK4/CDK6 and RB proteins drive the progression through the G1 phase of the cell cycle. In acute myeloid leukemia (AML), the activity of the CDK/Cyclin D complex is increased. The mechanism involved is unknown, as are the respective roles played by...
LA  - eng
KW  - AML
KW  - SRC
KW  - Oncogene
KW  - Palbociclib
KW  - Protein kinase
KW  - Signaling
KW  - Animals
KW  - Cell Line, Tumor
KW  - Cyclin-Dependent Kinase 6
KW  - Gene Expression Regulation, Leukemic
KW  - Humans
KW  - Leukemia, Myeloid, Acute
KW  - Mice
KW  - Mice, Inbred C57BL
KW  - Mice, Knockout
KW  - Mutation
KW  - Proto-Oncogene Proteins c-hck
KW  - Signal Transduction
KW  - Tandem Repeat Sequences
KW  - fms-Like Tyrosine Kinase 3
TI  - An essential pathway links FLT3-ITD, HCK and CDK6 in acute myeloid leukemia
TY  - journal article
ER  -