TY  - JOUR
AU  - Tirado-Velez, JM
AU  - Carreño, David
AU  - Sevillano, David
AU  - Alou, Luis
AU  - Yuste, Jose Enrique
AU  - de la Campa, Adela G
AU  - de la Campa
PY  - 2021
DO  - 10.3390/antibiotics10050573
SN  - 2079-6382
UR  - http://hdl.handle.net/20.500.12105/13871
AB  - Antibiotic resistance in Streptococcus pneumoniae has increased worldwide, making fluoroquinolones an alternative therapeutic option. Fluoroquinolones inhibit the type II DNA topoisomerases (topoisomerase IV and gyrase). In this study we have...
LA  - eng
PB  - Multidisciplinary Digital Publishing Institute (MDPI)
KW  - DNA topoisomerase I inhibitor
KW  - Streptococcus pneumoniae
KW  - Invasive pneumococcal disease
KW  - Resistance
KW  - Seconeolitsine
TI  - Seconeolitsine, the Novel Inhibitor of DNA Topoisomerase I, Protects against Invasive Pneumococcal Disease Caused by Fluoroquinolone-Resistant Strains
TY  - journal article
ER  -