TY  - JOUR
AU  - Torres-Ruiz, Raul
AU  - Rodriguez Perales, Sandra
PY  - 2015
DO  - 10.3390/ijms160922151
SN  - 1422-0067
UR  - http://hdl.handle.net/20.500.12105/5393
AB  - The cancer-modelling field is now experiencing a conversion with therecent emergence of the RNA-programmable CRISPR-Cas9 system, a flexiblemethodology to produce essentially any desired modification in thegenome. Cancer is a multistep process that...
LA  - eng
PB  - Multidisciplinary Digital Publishing Institute (MDPI)
KW  - CRISPR-Cas9 system
KW  - Cancer modelling
KW  - Gene mutations
KW  - Rearrangements
KW  - Genome engineering
KW  - ZINC-FINGER NUCLEASES
KW  - OFF-TARGET MUTATIONS
KW  - ONE-STEP GENERATION
KW  - IN-VIVO
KW  - HUMAN-CELLS
KW  - HUMAN GENOME
KW  - CHROMOSOMAL REARRANGEMENTS
KW  - CAS9 RIBONUCLEOPROTEINS
KW  - TUMOR-SUPPRESSOR
KW  - MAMMALIAN-CELLS
TI  - CRISPR-Cas9: A Revolutionary Tool for Cancer Modelling
TY  - journal article
ER  -