TY - GEN AU - Vázquez-Carballo, Cristina AU - Herencia, Carmen AU - Guerrero-Hue, Melania AU - García-Caballero, Cristina AU - Rayego-Mateos, Sandra AU - Morgado-Pascual, José Luis AU - Opazo-Ríos, Lucas AU - González-Guerrero, Cristian AU - Vallejo-Mudarra, Mercedes AU - Cortegano, Isabel AU - Gaspar, Maria Luisa AU - Andres, Belen de AU - Egido, Jesús AU - Moreno, Juan Antonio PY - 2022 DO - 10.1002/path.5995 UR - http://hdl.handle.net/20.500.12105/16027 AB - Massive intravascular hemolysis is a common characteristic of several pathologies. It is associated with the release of large quantities of heme into the circulation, promoting injury in vulnerable organs, mainly kidney, liver, and spleen. Heme... LA - eng PB - Wiley KW - TLR4 KW - Acute kidney injury KW - Heme KW - Hemoglobin KW - Inflammation KW - Intravascular hemolysis KW - Oxidative stress KW - Hemolysis KW - Toll-Like Receptor 4 KW - Animals KW - Disease Models, Animal KW - Heme KW - Inflammation KW - Mice KW - Mice, Knockout KW - NF-kappa B KW - Phenylhydrazines KW - Sulfonamides TI - Role of Toll-like receptor 4 in intravascular hemolysis-mediated injury TY - research article ER -