TY  - GEN
AU  - Daza-Cajigal, Vanessa
AU  - Albuquerque, Adriana S
AU  - Pearson, Joanna
AU  - Hinley, Jennifer
AU  - Mason, Andrew S
AU  - Stahlschmidt, Jens
AU  - Thrasher, Adrian J
AU  - Mishra, Vibhash
AU  - Southgate, Jennifer
AU  - Burns, Siobhan O
PY  - 2019
DO  - 10.3389/fimmu.2019.02065
SN  - 1664-3224
UR  - https://hdl.handle.net/20.500.12105/22717
AB  - Inherited Primary Immunodeficiency (PID) disorders are associated with increased risk of malignancy that may relate to impaired antitumor immune responses or a direct role for PID germline mutations in tumorigenesis. We recently identified germline...
LA  - eng
PB  - Frontiers Media
KW  - Bladder cancer
KW  - IFN gamma signaling
KW  - Immunodeficiency
KW  - JAK1
KW  - Urothelium
KW  - Urinary Bladder Neoplasms
KW  - Cytotoxicity, Immunologic
KW  - Epithelial Cells
KW  - Telomerase
KW  - Humans
KW  - Cell Line, Tumor
KW  - Disease Susceptibility
KW  - Lymphocytes
KW  - Biomarkers
KW  - Interferon-gamma
KW  - Immunohistochemistry
KW  - STAT1 Transcription Factor
KW  - Mucous Membrane
KW  - RNA, Messenger
KW  - Janus Kinase 1
KW  - Gene Expression Regulation, Neoplastic
TI  - Loss of Janus Associated Kinase 1 Alters Urothelial Cell Function and Facilitates the Development of Bladder Cancer
TY  - research article
ER  -