TY - JOUR AU - Alvarez-Prado, Angel Francisco AU - Perez-Duran, Pablo AU - Perez-Garcia, Arantxa AU - Benguria, Alberto AU - Torroja, Carlos AU - de Yebenes, Virginia G AU - Ramiro, Almudena R PY - 2018 DO - 10.1084/jem.20171738 SN - 0022-1007 UR - http://hdl.handle.net/20.500.12105/6545 AB - Activation-induced deaminase (AID) initiates antibody diversification in germinal center (GC) B cells through the deamination of cytosines on immunoglobulin genes. AID can also target other regions in the genome, triggering mutations or chromosome... LA - eng PB - Rockefeller University Press KW - INDUCED CYTIDINE DEAMINASE KW - B-CELL LYMPHOMAS KW - CLASS SWITCH RECOMBINATION KW - SEQUENCING REVEALS KW - GENOMIC INSTABILITY KW - SUPER-ENHANCERS KW - DEFICIENT MICE KW - DNA BREAKS KW - IG GENES KW - C-MYC TI - A broad atlas of somatic hypermutation allows prediction of activation-induced deaminase targets TY - journal article ER -