TY - GEN AU - Landa, Iñigo AU - Montero-Conde, Cristina AU - Malanga, Donatella AU - De Gisi, Silvia AU - Pita, Guillermo AU - Leandro-García, Luis-Javier AU - Inglada-Pérez, Lucía AU - Letón, Rocío AU - De Marco, Carmela AU - Rodriguez Antona, Cristina AU - Viglietto, Giuseppe AU - Robledo, Mercedes AU - Robledo Batanero, Mercedes PY - 2010 UR - https://hdl.handle.net/20.500.12105/27210 AB - The aim of this study is to assess if common genetic variants located in the CDKN1B locus, coding for the cell cycle inhibitor p27(Kip1), are involved in thyroid cancer susceptibility. Based on the literature and functional predictions, we selected... LA - eng PB - BIOSCIENTIFICA LTD KW - SINGLE-NUCLEOTIDE POLYMORPHISMS KW - LYMPH-NODE METASTASES KW - GENETIC ALTERATIONS KW - RET PROTOONCOGENE KW - INHIBITOR P27 KW - PHOSPHATIDYLINOSITOL 3-KINASE/AKT KW - TUMOR-SUPPRESSOR KW - P27KIP1 PROTEIN KW - DOWN-REGULATION KW - BREAST CANCER TI - Allelic variant at -79 (C>T) in CDKN1B (p27Kip1) confers an increased risk of thyroid cancer and alters mRNA levels. TY - research article ER -