TY - JOUR AU - LLanos, Susana AU - GarcĂ­a-Pedrero, Juana M AU - Morgado-Palacin, Lucia AU - Rodrigo, Juan P AU - Serrano Marugan, Manuel PY - 2016 DO - 10.1038/ncomms10438 SN - 2041-1723 UR - http://hdl.handle.net/20.500.12105/7870 AB - The levels, regulation and prognostic value of p21 in head and neck squamous cell carcinomas (HNSCC) has been puzzling for years. Here, we report a new mechanism of regulation of p21 by the mTORC1/4E-BP1 pathway. We find that non-phosphorylated 4E-BP1... LA - eng PB - Nature Publishing Group KW - Adaptor Proteins, Signal Transducing KW - Adult KW - Aged TI - Stabilization of p21 by mTORC1/4E-BP1 predicts clinical outcome of head and neck cancers TY - journal article ER -