TY - JOUR AU - Rodríguez-Díez, Esther AU - Quereda, Victor AU - Bellutti, Florian AU - Prchal-Murphy, Michaela AU - Partida, David AU - Eguren, Manuel AU - Kollmann, Karoline AU - Gómez de Cedrón, Marta AU - Dubus, Pierre AU - Cañamero, Marta AU - Martinez Garcia, Maria Dolores AU - Sexl, Veronika AU - Malumbres Martinez, Marcos PY - 2014 DO - 10.1182/blood-2014-02-555292 UR - http://hdl.handle.net/20.500.12105/17418 AB - Cdk4 and Cdk6 are related protein kinases that bind d-type cyclins and regulate cell-cycle progression. Cdk4/6 inhibitors are currently being used in advanced clinical trials and show great promise against many types of tumors. Cdk4 and Cdk6 are... LA - eng PB - Elsevier KW - Alleles KW - Animals KW - Carcinogenesis KW - Cell Death KW - Cell Line, Transformed KW - Cell Proliferation KW - Cyclin-Dependent Kinase 4 KW - Cyclin-Dependent Kinase 6 KW - Cyclin-Dependent Kinase Inhibitor Proteins KW - Fusion Proteins, bcr-abl KW - Gene Ontology KW - Hematopoiesis KW - Hematopoietic Stem Cells KW - Mice KW - Mutant Proteins TI - Cdk4 and Cdk6 cooperate in counteracting the INK4 family of inhibitors during murine leukemogenesis. TY - journal article ER -