TY - JOUR AU - Bejarano, Leire AU - Louzame, Jessica AU - Montero, Juán José AU - Megias Vazquez, Diego AU - Flores, Juana M AU - Blasco , MA PY - 2019 DO - 10.1016/j.isci.2019.08.012 SN - 25890042 UR - http://hdl.handle.net/20.500.12105/8315 AB - Telomeres are considered potential anti-cancer targets. Most studies have focused on telomerase inhibition, but this strategy has largely failed in clinical trials. Direct disruption of the shelterin complex through TRF1 inhibition can block... LA - eng PB - Cell Press KW - Cancer KW - Model Organism KW - Safety Assessment TI - Safety of Whole-Body Abrogation of the TRF1 Shelterin Protein in Wild-Type and Cancer-Prone Mouse Models TY - journal article ER -