TY - GEN AU - Martinez-Laso, Jorge AU - Cervera Hernandez, Isabel AU - Muñoz-Gómez, María José AU - Sánchez-Menéndez, Clara AU - Torres, Montserrat AU - Salamanca-Soto, Ana AU - Torres, Montserrat AU - Coiras, Mayte PY - 2025 DO - 10.1016/j.biochi.2025.09.003 UR - https://hdl.handle.net/20.500.12105/27040 AB - TLR8 and TLR9 are innate immune receptors belonging to the TLR family that are essential for viral recognition and early immune activation. Their dysfunction is linked to increased susceptibility to infections. TLR8 detects viral single- and... LA - eng PB - Elsevier KW - Alternative RNA splicing KW - Evolution KW - Isoforms KW - TLR8 KW - TLR9 KW - Alternative Splicing KW - Amino Acid Sequence KW - Evolution, Molecular KW - Humans KW - RNA, Messenger KW - Toll-Like Receptor 8 KW - Toll-Like Receptor 9 TI - Novel alternative transcripts of TLR8 and TLR9 reveal evolutionary pressure to conserve protein structure. TY - research article ER -