TY - GEN AU - Ruiz-Pinto, S AU - Pita, G AU - Patiño-García, Ana AU - García-Miguel, P AU - Alonso, Javier AU - Pérez-Martínez, A AU - Sastre, A AU - Gomez-Mariano, Gema Maria AU - Lissat, A AU - Scotlandi, K AU - Serra, M AU - Ladenstein, R AU - Lapouble, E AU - Pierron, G AU - Kontny, U AU - Picci, P AU - Kovar, H AU - Delattre, O AU - González-Neira, A PY - 2016 DO - 10.1093/annonc/mdw234 UR - http://hdl.handle.net/20.500.12105/17262 AB - Background: Despite the effectiveness of current treatment protocols for Ewing sarcoma (ES), many patients still experience relapse, and survival following recurrence is <15%. We aimed to identify genetic variants that predict treatment outcome in... LA - eng PB - Elsevier KW - Ewing sarcoma KW - Polymorphisms KW - Pharmacokinetic genes KW - Prognostic KW - Pathway-based approach KW - ATP Binding Cassette Transporter, Subfamily B KW - Adolescent KW - Adult KW - Child KW - Child, Preschool KW - Cytochrome P-450 CYP2C8 KW - Female KW - Genetic Association Studies KW - Genotype KW - Humans KW - Infant KW - Male KW - Multidrug Resistance-Associated Proteins KW - Neoplasm Recurrence, Local KW - Polymorphism, Single Nucleotide KW - Sarcoma, Ewing KW - Survival Analysis KW - Treatment Outcome KW - Young Adult TI - Identification of genetic variants in pharmacokinetic genes associated with Ewing Sarcoma treatment outcome TY - research article ER -