TY - GEN AU - Torrens-Mas, Margalida AU - Hernández-López, Reyniel AU - Oliver, Jordi AU - Roca, Pilar AU - Sastre-Serra, Jorge PY - 2018 DO - 10.1002/jcp.26443 UR - https://hdl.handle.net/20.500.12105/22505 AB - Sirtuin 3 (SIRT3) is the major mitochondria deacetylase and regulates ROS levels by targeting several key proteins, such as those involved in mitochondrial function and antioxidant defenses. This way, SIRT3 balances ROS production and scavenging and... LA - eng PB - Wiley KW - Antioxidants KW - Oxidative Stress KW - Mitochondria KW - Acetylation KW - Reactive Oxygen Species KW - Humans KW - Oxaliplatin KW - Cell Line, Tumor KW - Colonic Neoplasms KW - Apoptosis KW - Gene Expression KW - Superoxide Dismutase KW - Sirtuin 3 TI - Sirtuin 3 silencing improves oxaliplatin efficacy through acetylation of MnSOD in colon cancer TY - research article ER -