TY  - GEN
AU  - Cuadrado, Irene
AU  - Amesty, Ángel
AU  - Cedrón, Juan Carlos
AU  - Oberti, Juan Carlos
AU  - Estévez-Braun, Ana
AU  - Hortelano, Sonsoles
AU  - de Las Heras, Beatriz
PY  - 2018
DO  - 10.3390/molecules23123197
SN  - 1420-3049
UR  - http://hdl.handle.net/20.500.12105/9329
AB  - A series of nine derivatives (2⁻10) were prepared from the diterpene solidagenone (1) and their structures were elucidated by means of spectroscopic studies. Their ability to inhibit inflammatory responses elicited in peritoneal macrophages by TLR...
LA  - eng
PB  - Multidisciplinary Digital Publishing Institute (MDPI)
KW  - TLR4
KW  - Diterpenes
KW  - Inflammation
KW  - Molecular docking
KW  - Solidagenone derivatives
KW  - Animals
KW  - Anti-Inflammatory Agents
KW  - Cells, Cultured
KW  - Furans
KW  - Macrophage Activation
KW  - Macrophages, Peritoneal
KW  - Male
KW  - Mice
KW  - Mice, Inbred BALB C
KW  - Molecular Docking Simulation
KW  - Naphthalenes
KW  - Toll-Like Receptors
TI  - Semisynthesis and Inhibitory Effects of Solidagenone Derivatives on TLR-Mediated Inflammatory Responses
TY  - research article
ER  -