TY - JOUR AU - Huang, Yujie AU - Rajappa, Prajwal AU - Hu, Wenhuo AU - Hoffman, Caitlin AU - Cisse, Babacar AU - Kim, Joon-Hyung AU - Gorge, Emilie AU - Yanowitch, Rachel AU - Cope, William AU - Vartanian, Emma AU - Xu, Raymond AU - Zhang, Tuo AU - Pisapia, David AU - Xiang, Jenny AU - Huse, Jason AU - Matei, Irina AU - Peinado Selgas, Hector AU - Bromberg, Jacqueline AU - Holland, Eric AU - Ding, Bi-Sen AU - Rafii, Shahin AU - Lyden, David AU - Greenfield, Jeffrey PY - 2017 DO - 10.1172/JCI86443 SN - 0021-9738 UR - http://hdl.handle.net/20.500.12105/8388 AB - Tumors are capable of coopting hematopoietic cells to create a suitable microenvironment to support malignant growth. Here, we have demonstrated that upregulation of kinase insert domain receptor (KDR), also known as VEGFR2, in a myeloid cell... LA - eng PB - American Society for Clinical Investigation (ASCI) KW - Animals KW - Cell Line, Tumor KW - Granulocyte-Macrophage Colony-Stimulating Factor KW - Humans KW - Inhibitor of Differentiation Protein 2 KW - Mice KW - Mice, Transgenic KW - Neoplasm Proteins KW - Signal Transduction KW - Transforming Growth Factor beta KW - Vascular Endothelial Growth Factor Receptor-2 KW - Bone Marrow Cells KW - Glioma KW - Myeloid Cells KW - Neovascularization, Pathologic TI - A proangiogenic signaling axis in myeloid cells promotes malignant progression of glioma TY - journal article ER -