TY  - GEN
AU  - Carmona, Rita
AU  - Cañete, Ana
AU  - Cano, Elena
AU  - Ariza, Laura
AU  - Rojas, Anabel
AU  - Muñoz-Chápuli, Ramon
PY  - 2016
DO  - 10.7554/eLife.16009
UR  - http://hdl.handle.net/20.500.12105/17156
AB  - Congenital diaphragmatic hernia (CDH) is a severe birth defect. Wt1-null mouse embryos develop CDH but the mechanisms regulated by WT1 are unknown. We have generated a murine model with conditional deletion of WT1 in the lateral plate mesoderm, using...
LA  - eng
KW  - Gata4
KW  - Wilms' tumor suppressor gene
KW  - congenital diaphragmatic hernia
KW  - developmental biology
KW  - epithelial-mesenchymal transition
KW  - human biology
KW  - medicine
KW  - mouse
KW  - stem cells
KW  - Animals
KW  - Diaphragm
KW  - Disease Models, Animal
KW  - Hernias, Diaphragmatic, Congenital
KW  - Mesoderm
KW  - Mice
KW  - Mice, Knockout
KW  - Repressor Proteins
KW  - Sequence Deletion
KW  - WT1 Proteins
TI  - Conditional deletion of WT1 in the septum transversum mesenchyme causes congenital diaphragmatic hernia in mice.
TY  - research article
ER  -