TY  - JOUR
AU  - Xiong, Huizhong
AU  - Mancini, Maicol
AU  - Gobert, Michael
AU  - Shen, Shiqian
AU  - Furtado, Glaucia C
AU  - Lira, Sergio A
AU  - Parkhurst, Christopher N
AU  - Garambois, Veronique
AU  - Brengues, Muriel
AU  - Tadokoro, Carlos E
AU  - Trimarchi, Thomas
AU  - Gómez-López, Gonzalo
AU  - Singh, Amartya
AU  - Khiabanian, Hossein
AU  - Minuzzo, Sonia
AU  - Indraccolo, Stefano
AU  - Lobry, Camille
AU  - Aifantis, Iannis
AU  - Herranz, Daniel
AU  - Lafaille, Juan J
AU  - Maraver, Antonio
PY  - 2021
DO  - 10.7150/thno.48067
UR  - http://hdl.handle.net/20.500.12105/13341
AB  - The Notch pathway is highly active in almost all patients with T-cell acute lymphoblastic leukemia (T-ALL), but the implication of Notch ligands in T-ALL remains underexplored. Methods: We used a genetic mouse model of Notch ligand delta like 4...
LA  - eng
PB  - Ivyspring International Publisher
KW  - Gene Expression Regulation, Neoplastic
KW  - Adaptor Proteins, Signal Transducing
KW  - Animals
KW  - Apoptosis
KW  - Biomarkers, Tumor
KW  - Calcium-Binding Proteins
KW  - Cell Proliferation
KW  - Female
KW  - Humans
KW  - Mice
KW  - Mice, Inbred NOD
KW  - Mice, SCID
KW  - Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
KW  - Receptors, Notch
KW  - Spleen
KW  - Tumor Cells, Cultured
KW  - Xenograft Model Antitumor Assays
TI  - Spleen plays a major role in DLL4-driven acute T-cell lymphoblastic leukemia.
TY  - journal article
ER  -