TY - JOUR AU - Muñoz-Lorente, Miguel A AU - Martinez Rodriguez , Paula AU - Tejera, Agueda AU - Whittemore, Kurt AU - Moisés-Silva, Ana Carolina AU - Bosch, Fàtima AU - Blasco , MA PY - 2018 DO - 10.1371/journal.pgen.1007562 SN - 1553-7404 UR - http://hdl.handle.net/20.500.12105/6599 AB - Short and dysfunctional telomeres are sufficient to induce a persistent DNA damage response at chromosome ends, which leads to the induction of senescence and/or apoptosis and to various age-related conditions, including a group of diseases known as... LA - eng PB - Public Library of Science (PLOS) KW - TERT PROMOTER MUTATIONS KW - MOUSE TELOMERASE KW - CHROMOSOMAL INSTABILITY KW - CELLULAR SENESCENCE KW - BLADDER-CANCER KW - DNA-DAMAGE KW - MICE KW - ADULT KW - EXPRESSION TI - AAV9-mediated telomerase activation does not accelerate tumorigenesis in the context of oncogenic K-Ras-induced lung cancer TY - journal article ER -