TY - GEN AU - Noriega, Victor AU - Martinez-Laperche, Carolina AU - Buces, Elena AU - Sanchez-Hernandez, Noemi AU - Martin-Antonio, Beatriz AU - Guillem, Vicent AU - Bosch-Vizcaya, Anna AU - Bento, Leyre AU - Gonzalez-Rivera, Milagros AU - Balsalobre, Pascual AU - Kwon, Mi AU - Serrano, David AU - Gayoso, Jorge AU - de la Cámara, Rafael AU - Brunet, Salut AU - Rojas-Contreras, Rafael AU - Nieto, Jose B. AU - Martinez, Carmen AU - Gonzalez, Marcos AU - Espigado, Ildefonso AU - Vallejo, Juan C. AU - Sampol Mayol, Antonia AU - Jimenez-Velasco, Antonio AU - Urbano-Ispizua, Alvaro AU - Solano, Carlos AU - Gallardo, David AU - Diez-Martin, Jose L AU - Buno, Ismael AU - Spanish Hematopoietic Stem Cell Tr PY - 2015 DO - 10.1371/journal.pone.0140454 SN - 1932-6203 UR - http://hdl.handle.net/20.500.12105/20154 AB - The FOXP3 gene encodes for a protein (Foxp3) involved in the development and functional activity of regulatory T cells (CD4+/CD25+/Foxp3+), which exert regulatory and suppressive roles over the immune system. After allogeneic stem cell... LA - eng PB - Public Library of Science (PLOS) KW - Forkhead Transcription Factors KW - Genotype KW - Aged KW - Young Adult KW - Hematopoietic Stem Cell Transplantation KW - Transplantation, Homologous KW - Adult KW - Humans KW - Graft vs Leukemia Effect KW - Middle Aged KW - Promoter Regions, Genetic KW - Graft vs Host Disease KW - Male KW - Tissue Donors KW - Female KW - Genetic Association Studies KW - Survival Analysis KW - Polymorphism, Genetic TI - The Genotype of the Donor for the (GT)(n) Polymorphism in the Promoter/Enhancer of FOXP3 Is Associated with the Development of Severe Acute GVHD but Does Not Affect the GVL Effect after Myeloablative HLA-Identical Allogeneic Stem Cell Transplantation TY - research article ER -