TY - JOUR AU - Sastré-Velásquez, Luis Enrique AU - Dallemulle, Alex AU - Kühbacher, Alexander AU - Baldin, Clara AU - Alcazar-Fuoli, Laura AU - Niedrig, Anna AU - Müller, Christoph AU - Gsaller, Fabio PY - 2022 DO - 10.1371/journal.ppat.1011066 UR - http://hdl.handle.net/20.500.12105/16002 AB - Invasive aspergillosis remains one of the most devastating fungal diseases and is predominantly linked to infections caused by the opportunistic human mold pathogen Aspergillus fumigatus. Major treatment regimens for the disease comprise the... LA - eng PB - Public Library of Science (PLOS) KW - Antineoplastic Agents KW - Aspergillosis KW - Animals KW - Humans KW - Flucytosine KW - Antifungal Agents KW - Antimetabolites KW - Fluorouracil KW - Aspergillus fumigatus KW - Drug Resistance, Fungal KW - Mammals TI - The fungal expel of 5-fluorocytosine derived fluoropyrimidines mitigates its antifungal activity and generates a cytotoxic environment TY - journal article ER -