TY  - JOUR
AU  - Richart, Laia
AU  - Lapi, Eleonora
AU  - Pancaldi, Vera
AU  - Cuenca-Ardura, Mirabai
AU  - Pau, Enrique Carrillo-de-Santa
AU  - Madrid-Mencía, Miguel
AU  - Neyret-Kahn, Hélène
AU  - Radvanyi, François
AU  - Rodríguez, Juan Antonio
AU  - Cuartero, Yasmina
AU  - Serra, François
AU  - Le Dily, François
AU  - Valencia, Alfonso
AU  - Marti-Renom, Marc A
AU  - Real Arribas, Francisco
PY  - 2021
DO  - 10.1093/nar/gkab864
UR  - http://hdl.handle.net/20.500.12105/13723
AB  - Cohesin exists in two variants containing STAG1 or STAG2. STAG2 is one of the most mutated genes in cancer and a major bladder tumor suppressor. Little is known about how its inactivation contributes to tumorigenesis. Here, we analyze the genomic...
LA  - eng
PB  - Oxford University Press
KW  - COHESIN COMPLEX
KW  - MUTATIONS
KW  - GENES
KW  - REVEALS
KW  - INACTIVATION
KW  - PRINCIPLES
KW  - COMPONENTS
KW  - ANEUPLOIDY
KW  - ELEMENTS
KW  - DOMAIN
KW  - Loss of Function Mutation
KW  - Transcription, Genetic
KW  - Base Sequence
KW  - Cell Cycle Proteins
KW  - Cell Line, Tumor
KW  - Chromatin
KW  - Chromosomal Proteins, Non-Histone
KW  - DNA, Neoplasm
KW  - Gene Expression Profiling
KW  - Gene Expression Regulation, Neoplastic
KW  - Gene Ontology
KW  - HEK293 Cells
KW  - Histones
KW  - Humans
KW  - Molecular Sequence Annotation
KW  - Nuclear Proteins
KW  - RNA, Small Interfering
KW  - Signal Transduction
KW  - Urinary Bladder Neoplasms
TI  - STAG2 loss-of-function affects short-range genomic contacts and modulates the basal-luminal transcriptional program of bladder cancer cells.
TY  - journal article
ER  -