TY - GEN AU - Abad-Perez, Daniel AU - Novella-Arribas, Blanca AU - Rodríguez-Salvanés, Francisco AU - Sanchez-Gomez, Luis Maria AU - García-Polo, Iluminada AU - Verge-González, Carmen AU - Suárez-Fernández, Carmen PY - 2013 DO - 10.1186/1745-6215-14-388 SN - 1745-6215 UR - http://hdl.handle.net/20.500.12105/6822 AB - BACKGROUND: Isolated systolic hypertension is a highly prevalent disease among the elderly. The little available evidence on the efficacy of nitrates for treating the disease is based on small experimental studies. METHODS/DESIGN: We performed a... LA - eng PB - BioMed Central (BMC) KW - Hypertension KW - Nitrates KW - Older people KW - Systolic-hypertension KW - Administration, Oral KW - Aged KW - Antihypertensive Agents KW - Blood Pressure KW - Blood Pressure Monitoring, Ambulatory KW - Clinical Protocols KW - Delayed-Action Preparations KW - Double-Blind Method KW - Elasticity KW - Humans KW - Hypertension KW - Isosorbide Dinitrate KW - Pulse Wave Analysis KW - Spain KW - Time Factors KW - Treatment Outcome KW - Vascular Stiffness KW - Vasodilator Agents KW - Research Design TI - Effect of oral nitrates on pulse pressure and arterial elasticity in patients aged over 65 years with refractory isolated systolic hypertension: study protocol for a randomized controlled trial TY - research article ER -