TY - JOUR AU - Gomez-Mauricio, Guadalupe AU - Moscoso, Isabel AU - Martin-Cancho, Maria-Fernanda AU - Crisostomo, Veronica AU - Prat-Vidal, Cristina AU - Baez-Diaz, Claudia AU - Sánchez-Margallo, Francisco Miguel AU - Bernad, Antonio PY - 2016 DO - 10.1186/s13287-016-0350-z SN - 1757-6512 UR - http://hdl.handle.net/20.500.12105/5210 AB - Background: Insulin-like growth factor 1 (IGF-1) and hepatocyte growth factor (HGF) are among the most promising growth factors for promoting cardiorepair. Here, we evaluated the combination of cell-and gene-based therapy using mesenchymal stem cells... LA - eng PB - BioMed Central (BMC) KW - Mesenchymal stem cells KW - HGF KW - IGF-1 KW - Acute myocardial infarction KW - Porcine model KW - Gene therapy KW - Cell therapy KW - HEPATOCYTE GROWTH-FACTOR KW - ELEVATION MYOCARDIAL-INFARCTION KW - RANDOMIZED PHASE-1 TRIAL KW - PROGENITOR CELLS KW - INTRACORONARY INJECTION KW - HEART-FAILURE KW - IN-VITRO KW - REPAIR KW - THERAPY KW - ACTIVATION TI - Combined administration of mesenchymal stem cells overexpressing IGF-1 and HGF enhances neovascularization but moderately improves cardiac regeneration in a porcine model TY - journal article ER -