TY - GEN AU - González-Cofrade, Laura AU - Oramas-Royo, Sandra AU - Cuadrado, Irene AU - Amesty, Ángel AU - Hortelano, Sonsoles AU - Estévez-Braun, Ana AU - de Las Heras, Beatriz PY - 2020 DO - 10.1021/acs.jnatprod.0c00200 UR - http://hdl.handle.net/20.500.12105/17375 AB - The NLRP3 inflammasome plays a critical role in inflammation-mediated human diseases and represents a promising drug target for novel anti-inflammatory therapies. Hispanolone is a labdane diterpenoid isolated from the aerial parts of Ballota species.... LA - eng PB - ACS Publications KW - Animals KW - Diterpenes KW - Humans KW - Inflammasomes KW - Inflammation KW - Molecular Structure KW - NLR Family, Pyrin Domain-Containing 3 Protein KW - Structure-Activity Relationship TI - Dehydrohispanolone Derivatives Attenuate the Inflammatory Response through the Modulation of Inflammasome Activation TY - research article ER -