TY  - GEN
AU  - Sanchez-Varo, Raquel
AU  - Sanchez-Mejias, Elisabeth
AU  - Fernandez-Valenzuela, Juan Jose
AU  - De Castro, Vanessa
AU  - Mejias-Ortega, Marina
AU  - Gomez-Arboledas, Angela
AU  - Jimenez, Sebastian
AU  - Sanchez-Mico, Maria Virtudes
AU  - Trujillo-Estrada, Laura
AU  - Moreno-Gonzalez, Ines
AU  - Baglietto-Vargas, David
AU  - Vizuete, Marisa
AU  - Davila, Jose Carlos
AU  - Vitorica, Javier
AU  - Gutierrez, Antonia
PY  - 2021
DO  - 10.3389/fnins.2021.752594
UR  - http://hdl.handle.net/20.500.12105/18497
AB  - Alzheimer's disease (AD) is a devastating neurodegenerative disorder characterized by initial memory impairments that progress to dementia. In this sense, synaptic dysfunction and loss have been established as the pathological features that best...
LA  - eng
PB  - Frontiers Media
KW  - Alzheimer’s disease
KW  - Synaptic pathology
KW  - Hippocampus
KW  - Transgenic mice (Tg)
KW  - Amyloid
KW  - Oligomers
KW  - Enfermedad de Alzheimer
KW  - Hipocampo
KW  - Ratones transgénicos
KW  - Amiloide
KW  - Morfolinos
KW  - Humans
KW  - Infant
KW  - Plaque, Amyloid
KW  - Alzheimer Disease
KW  - Neurofibrillary Tangles
KW  - Presynaptic Terminals
KW  - Neurites
KW  - Astrocytes
KW  - Electrons
KW  - Microglia
KW  - Brain
KW  - Hippocampus
KW  - Microscopy, Electron
TI  - Plaque-Associated Oligomeric Amyloid-Beta Drives Early Synaptotoxicity in APP/PS1 Mice Hippocampus: Ultrastructural Pathology Analysis
TY  - research article
ER  -