TY - GEN AU - Rodriguez, Carlos F AU - Escudero-Bravo, Paloma AU - Díaz, Lucía AU - Bartoccioni, Paola AU - García-Martín, Carmen AU - Gilabert, Joan G AU - Boskovic, Jasminka AU - Guallar, Víctor AU - Errasti-Murugarren, Ekaitz AU - Llorca Blanco, Oscar Antonio AU - Palacín, Manuel PY - 2021 DO - 10.1073/pnas.2113573118 UR - https://hdl.handle.net/20.500.12105/23089 AB - Despite having similar structures, each member of the heteromeric amino acid transporter (HAT) family shows exquisite preference for the exchange of certain amino acids. Substrate specificity determines the physiological function of each HAT and their... LA - eng PB - National Academy of Sciences KW - Adaptor Proteins, Signal Transducing KW - Amino Acid Transport Systems KW - Amino Acid Transport Systems, Neutral KW - Amino Acids KW - Amino Acids, Neutral KW - Biological Transport KW - Cryoelectron Microscopy KW - Fusion Regulatory Protein 1, Heavy Chain KW - HeLa Cells KW - Humans KW - Large Neutral Amino Acid-Transporter 1 KW - Protein Domains KW - Structure-Activity Relationship KW - Substrate Specificity TI - Structural basis for substrate specificity of heteromeric transporters of neutral amino acids. TY - research article ER -