TY  - JOUR
AU  - Sanchez-Burgos, Laura
AU  - Navarro-González, Belén
AU  - García-Martín, Santiago
AU  - Sirozh, Oleksandra
AU  - Mota-Pino, Jorge
AU  - Fueyo-Marcos, Elena
AU  - Tejero, Héctor
AU  - Antón, Marta Elena
AU  - Murga, Matilde
AU  - Al-Shahrour, Fatima
AU  - Fernandez-Capetillo, Oscar
PY  - 2022
DO  - 10.15252/emmm.202215855
UR  - http://hdl.handle.net/20.500.12105/17693
AB  - FBXW7 is one of the most frequently mutated tumor suppressors, deficiency of which has been associated with resistance to some anticancer therapies. Through bioinformatics and genome-wide CRISPR screens, we here reveal that FBXW7 deficiency leads to...
LA  - eng
PB  - EMBO Press
KW  - Protein Biosynthesis
KW  - Proteomics
KW  - Cell Line, Tumor
KW  - F-Box-WD Repeat-Containing Protein 7
KW  - Mutation
KW  - Up-Regulation
TI  - Activation of the integrated stress response is a vulnerability for multidrug-resistant FBXW7-deficient cells.
TY  - journal article
ER  -